Research Interest    

Misfolding and Protein Conformational Diseases

  • Self-assemblies of the misfolded proteins and their cytotoxicities

  • Mechanism of Humanin antagonizing neurotoxicities in AD and Prion

  • Protein-membrane interactions

Self-assembled Nanowire and Molecular Motor

  • Mechanism of the one-dimensional self-assemblies of de novo designed peptide as the building block

  • Nanowirs array and functionalization

  • Kinesin/tubulin-based molecular motor

Nanoparticle-based Probes for Imaging

  • Preparation of inorganic nanoparticles and their bioconjugation

  • Quantum dots as probes for molecular imaging in live cells

  • Quantum dots as a model for biosafety evaluation

Single-molecule & Nanobiology Laboratory (All right reserved by SNL)